Drug interactions for the following drug(s)
Spironolactone may decrease the vasoconstricting activities of Phenylephrine.
Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.
Drug1 (rxcui = 198223, name = Spironolactone 50 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 1043543, name = Dextromethorphan Hydrobromide 1 MG/ML / Guaifenesin 20 MG/ML / Phenylephrine Hydrochloride 0.5 MG/ML Oral Solution, tty = SCD). Drug1 is resolved to Phenylephrine, Drug2 is resolved to Spironolactone and interaction asserted in DrugBank between Phenylephrine and Spironolactone.