Drug interactions for the following drug(s)

Interactions between your selected drugs

Hydrochlorothiazide may increase the excretion rate of Trametinib which could result in a lower serum level and potentially a reduction in efficacy.

The therapeutic efficacy of Hydrochlorothiazide can be decreased when used in combination with Celecoxib.

Celecoxib may decrease the excretion rate of Trametinib which could result in a higher serum level.

The metabolism of Oxycodone can be increased when combined with Trametinib.

The metabolism of Oxycodone can be decreased when combined with Celecoxib.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Interactions between your selected drugs

Drug1 (rxcui = 197886, name = Hydrochlorothiazide 12.5 MG / Lisinopril 20 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 1425104, name = trametinib 0.5 MG Oral Tablet, tty = SCD). Drug1 is resolved to Hydrochlorothiazide, Drug2 is resolved to trametinib and interaction asserted in DrugBank between Hydrochlorothiazide and Trametinib. Drug1 is resolved to trametinib, Drug2 is resolved to Lisinopril Anhydrous and interaction asserted in DrugBank between Trametinib and Lisinopril. Drug1 is resolved to Lisinopril, Drug2 is resolved to trametinib and interaction asserted in DrugBank between Lisinopril and Trametinib.

Drug1 (rxcui = 197886, name = Hydrochlorothiazide 12.5 MG / Lisinopril 20 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 213469, name = celecoxib 200 MG Oral Capsule [Celebrex], tty = SBD). Drug1 is resolved to Hydrochlorothiazide, Drug2 is resolved to celecoxib and interaction asserted in DrugBank between Hydrochlorothiazide and Celecoxib. Drug1 is resolved to Lisinopril, Drug2 is resolved to celecoxib and interaction asserted in DrugBank between Lisinopril and Celecoxib. Drug1 is resolved to celecoxib, Drug2 is resolved to Lisinopril Anhydrous and interaction asserted in DrugBank between Celecoxib and Lisinopril.

Drug1 (rxcui = 213469, name = celecoxib 200 MG Oral Capsule [Celebrex], tty = SBD). Drug2 (rxcui = 1425104, name = trametinib 0.5 MG Oral Tablet, tty = SCD). Drug1 is resolved to celecoxib, Drug2 is resolved to trametinib and interaction asserted in DrugBank between Celecoxib and Trametinib.

Drug1 (rxcui = 1425104, name = trametinib 0.5 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 1860137, name = Abuse-Deterrent 12 HR Oxycodone Hydrochloride 40 MG Extended Release Oral Tablet, tty = SCD). Drug1 is resolved to Oxycodone, Drug2 is resolved to trametinib and interaction asserted in DrugBank between Oxycodone and Trametinib.

Drug1 (rxcui = 213469, name = celecoxib 200 MG Oral Capsule [Celebrex], tty = SBD). Drug2 (rxcui = 1860137, name = Abuse-Deterrent 12 HR Oxycodone Hydrochloride 40 MG Extended Release Oral Tablet, tty = SCD). Drug1 is resolved to Oxycodone, Drug2 is resolved to celecoxib and interaction asserted in DrugBank between Oxycodone and Celecoxib.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.