Drug interactions for the following drug(s)

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Interactions between your selected drugs

Moderate

Diphenhydramine<>Tramadol

Applies to: traMADol HCl 100 MG 24HR Extended Release Oral Tablet <> Diphenhydramine Hydrochloride 50 MG Oral Capsule

The therapeutic efficacy of Tramadol can be decreased when used in combination with Diphenhydramine.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Interactions between your selected drugs

Moderate

Diphenhydramine<>Tramadol

Applies to: traMADol HCl 100 MG 24HR Extended Release Oral Tablet <> Diphenhydramine Hydrochloride 50 MG Oral Capsule

Drug1 (rxcui = 833709, name = 24 HR tramadol hydrochloride 100 MG Extended Release Oral Tablet, tty = SCD). Drug2 (rxcui = 1020477, name = Diphenhydramine Hydrochloride 50 MG Oral Capsule, tty = SCD). Drug1 is resolved to Diphenhydramine, Drug2 is resolved to Tramadol and interaction asserted in DrugBank between Diphenhydramine and Tramadol.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

DrugInteractionChecker.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex® (updated Sep 28th, 2016), Cerner Multum™ (updated Oct 2nd, 2016), Wolters Kluwer™ (updated Oct 1st, 2016) and others. To view content sources and attributions, please refer to our editorial policy.