Drug interactions for the following drug(s)

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Interactions between your selected drugs

Moderate

diclofenac<>tramadol

Applies to: tramadol hydrochloride 100 MG 24 HR Extended Release Oral Tablet <> Diclofenac Sodium 50 MG Delayed Release Oral Tablet

Diclofenac may decrease the excretion rate of Tramadol which could result in a higher serum level.

Moderate

orphenadrine<>tramadol

Applies to: tramadol hydrochloride 100 MG 24 HR Extended Release Oral Tablet <> orphenadrine citrate 100 MG 12 HR Extended Release Oral Tablet

The metabolism of Orphenadrine can be decreased when combined with Tramadol.

Moderate

diclofenac<>orphenadrine

Applies to: Diclofenac Sodium 50 MG Delayed Release Oral Tablet <> orphenadrine citrate 100 MG 12 HR Extended Release Oral Tablet

The metabolism of Diclofenac can be decreased when combined with Orphenadrine.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Interactions between your selected drugs

Moderate

diclofenac<>tramadol

Applies to: tramadol hydrochloride 100 MG 24 HR Extended Release Oral Tablet <> Diclofenac Sodium 50 MG Delayed Release Oral Tablet

Drug1 (rxcui = 833709, name = 24 HR tramadol hydrochloride 100 MG Extended Release Oral Tablet, tty = SCD). Drug2 (rxcui = 855906, name = diclofenac sodium 50 MG Delayed Release Oral Tablet, tty = SCD). Drug1 is resolved to diclofenac, Drug2 is resolved to tramadol and interaction asserted in DrugBank between Diclofenac and Tramadol.

Moderate

orphenadrine<>tramadol

Applies to: tramadol hydrochloride 100 MG 24 HR Extended Release Oral Tablet <> orphenadrine citrate 100 MG 12 HR Extended Release Oral Tablet

Drug1 (rxcui = 833709, name = 24 HR tramadol hydrochloride 100 MG Extended Release Oral Tablet, tty = SCD). Drug2 (rxcui = 994521, name = 12 HR orphenadrine citrate 100 MG Extended Release Oral Tablet, tty = SCD). Drug1 is resolved to orphenadrine, Drug2 is resolved to tramadol and interaction asserted in DrugBank between Orphenadrine and Tramadol.

Moderate

diclofenac<>orphenadrine

Applies to: Diclofenac Sodium 50 MG Delayed Release Oral Tablet <> orphenadrine citrate 100 MG 12 HR Extended Release Oral Tablet

Drug1 (rxcui = 855906, name = diclofenac sodium 50 MG Delayed Release Oral Tablet, tty = SCD). Drug2 (rxcui = 994521, name = 12 HR orphenadrine citrate 100 MG Extended Release Oral Tablet, tty = SCD). Drug1 is resolved to diclofenac, Drug2 is resolved to orphenadrine and interaction asserted in DrugBank between Diclofenac and Orphenadrine.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.