Drug interactions for the following drug(s)

Interactions between your selected drugs

The therapeutic efficacy of Metformin can be decreased when used in combination with Levothyroxine.

The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Pioglitazone.

The risk or severity of hypoglycemia can be increased when Glimepiride is combined with Metformin.

Cephalexin may decrease the excretion rate of Metformin which could result in a higher serum level.

Cephalexin may decrease the excretion rate of Metformin which could result in a higher serum level.

The therapeutic efficacy of Glimepiride can be decreased when used in combination with Levothyroxine.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Interactions between your selected drugs

Drug1 (rxcui = 860975, name = 24 HR metformin hydrochloride 500 MG Extended Release Oral Tablet, tty = SCD). Drug2 (rxcui = 966201, name = levothyroxine sodium 0.15 MG Oral Tablet [Synthroid], tty = SBD). Drug1 is resolved to metformin, Drug2 is resolved to levothyroxine and interaction asserted in DrugBank between Metformin and Levothyroxine.

Drug1 (rxcui = 966201, name = levothyroxine sodium 0.15 MG Oral Tablet [Synthroid], tty = SBD). Drug2 (rxcui = 312441, name = pioglitazone 45 MG Oral Tablet, tty = SCD). Drug1 is resolved to levothyroxine, Drug2 is resolved to pioglitazone and interaction asserted in DrugBank between Levothyroxine and Pioglitazone.

Drug1 (rxcui = 860975, name = 24 HR metformin hydrochloride 500 MG Extended Release Oral Tablet, tty = SCD). Drug2 (rxcui = 153845, name = glimepiride 4 MG Oral Tablet [Amaryl], tty = SBD). Drug1 is resolved to metformin, Drug2 is resolved to glimepiride and interaction asserted in DrugBank between Metformin and Glimepiride.

Drug1 (rxcui = 860975, name = 24 HR metformin hydrochloride 500 MG Extended Release Oral Tablet, tty = SCD). Drug2 (rxcui = 309114, name = cephalexin 500 MG Oral Capsule, tty = SCD). Drug1 is resolved to metformin, Drug2 is resolved to cephalexin anhydrous and interaction asserted in DrugBank between Metformin and Cephalexin.

Drug1 (rxcui = 309114, name = cephalexin 500 MG Oral Capsule, tty = SCD). Drug2 (rxcui = 860975, name = 24 HR metformin hydrochloride 500 MG Extended Release Oral Tablet, tty = SCD). Drug1 is resolved to cephalexin, Drug2 is resolved to metformin and interaction asserted in DrugBank between Cephalexin and Metformin.

Drug1 (rxcui = 966201, name = levothyroxine sodium 0.15 MG Oral Tablet [Synthroid], tty = SBD). Drug2 (rxcui = 153845, name = glimepiride 4 MG Oral Tablet [Amaryl], tty = SBD). Drug1 is resolved to levothyroxine, Drug2 is resolved to glimepiride and interaction asserted in DrugBank between Levothyroxine and Glimepiride.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.