Drug interactions for the following drug(s)

Interactions between your selected drugs

The serum concentration of Digoxin can be increased when it is combined with Spironolactone.

The serum concentration of Digoxin can be increased when it is combined with Simvastatin.

The therapeutic efficacy of Metformin can be increased when used in combination with Carvedilol.

Digoxin may decrease the excretion rate of Warfarin which could result in a higher serum level.

Spironolactone may increase the excretion rate of Metformin which could result in a lower serum level and potentially a reduction in efficacy.

The metabolism of Simvastatin can be decreased when combined with Carvedilol.

The metabolism of Carvedilol can be decreased when combined with Warfarin.

The risk or severity of hyperkalemia can be increased when Spironolactone is combined with Carvedilol.

Metformin may increase the hypolipidaemic activities of Simvastatin.

Simvastatin may increase the anticoagulant activities of Warfarin.

The metabolism of Simvastatin can be decreased when combined with Spironolactone.

The serum concentration of Digoxin can be increased when it is combined with Metformin.

The metabolism of Warfarin can be decreased when combined with Spironolactone.

The serum concentration of Digoxin can be increased when it is combined with Carvedilol.

Metformin may decrease the excretion rate of Warfarin which could result in a higher serum level.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Interactions between your selected drugs

Drug1 (rxcui = 104208, name = 2 ML digoxin 0.25 MG/ML Injection, tty = SCD). Drug2 (rxcui = 198223, name = spironolactone 50 MG Oral Tablet, tty = SCD). Drug1 is resolved to digoxin, Drug2 is resolved to spironolactone and interaction asserted in DrugBank between Digoxin and Spironolactone.

Drug1 (rxcui = 104208, name = 2 ML digoxin 0.25 MG/ML Injection, tty = SCD). Drug2 (rxcui = 198211, name = simvastatin 40 MG Oral Tablet, tty = SCD). Drug1 is resolved to digoxin, Drug2 is resolved to simvastatin and interaction asserted in DrugBank between Digoxin and Simvastatin.

Drug1 (rxcui = 200031, name = carvedilol 6.25 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 860975, name = 24 HR metformin hydrochloride 500 MG Extended Release Oral Tablet, tty = SCD). Drug1 is resolved to metformin, Drug2 is resolved to carvedilol and interaction asserted in DrugBank between Metformin and Carvedilol.

Drug1 (rxcui = 104208, name = 2 ML digoxin 0.25 MG/ML Injection, tty = SCD). Drug2 (rxcui = 855312, name = warfarin sodium 2.5 MG Oral Tablet, tty = SCD). Drug1 is resolved to digoxin, Drug2 is resolved to warfarin and interaction asserted in DrugBank between Digoxin and Warfarin.

Drug1 (rxcui = 198223, name = spironolactone 50 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 860975, name = 24 HR metformin hydrochloride 500 MG Extended Release Oral Tablet, tty = SCD). Drug1 is resolved to metformin, Drug2 is resolved to spironolactone and interaction asserted in DrugBank between Metformin and Spironolactone.

Drug1 (rxcui = 198211, name = simvastatin 40 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 200031, name = carvedilol 6.25 MG Oral Tablet, tty = SCD). Drug1 is resolved to carvedilol, Drug2 is resolved to simvastatin and interaction asserted in DrugBank between Carvedilol and Simvastatin.

Drug1 (rxcui = 200031, name = carvedilol 6.25 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 855312, name = warfarin sodium 2.5 MG Oral Tablet, tty = SCD). Drug1 is resolved to warfarin, Drug2 is resolved to carvedilol and interaction asserted in DrugBank between Warfarin and Carvedilol.

Drug1 (rxcui = 198223, name = spironolactone 50 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 200031, name = carvedilol 6.25 MG Oral Tablet, tty = SCD). Drug1 is resolved to spironolactone, Drug2 is resolved to carvedilol and interaction asserted in DrugBank between Spironolactone and Carvedilol.

Drug1 (rxcui = 198211, name = simvastatin 40 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 860975, name = 24 HR metformin hydrochloride 500 MG Extended Release Oral Tablet, tty = SCD). Drug1 is resolved to metformin, Drug2 is resolved to simvastatin and interaction asserted in DrugBank between Metformin and Simvastatin.

Drug1 (rxcui = 198211, name = simvastatin 40 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 855312, name = warfarin sodium 2.5 MG Oral Tablet, tty = SCD). Drug1 is resolved to warfarin, Drug2 is resolved to simvastatin and interaction asserted in DrugBank between Warfarin and Simvastatin.

Drug1 (rxcui = 198211, name = simvastatin 40 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 198223, name = spironolactone 50 MG Oral Tablet, tty = SCD). Drug1 is resolved to spironolactone, Drug2 is resolved to simvastatin and interaction asserted in DrugBank between Spironolactone and Simvastatin.

Drug1 (rxcui = 104208, name = 2 ML digoxin 0.25 MG/ML Injection, tty = SCD). Drug2 (rxcui = 860975, name = 24 HR metformin hydrochloride 500 MG Extended Release Oral Tablet, tty = SCD). Drug1 is resolved to digoxin, Drug2 is resolved to metformin and interaction asserted in DrugBank between Digoxin and Metformin.

Drug1 (rxcui = 198223, name = spironolactone 50 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 855312, name = warfarin sodium 2.5 MG Oral Tablet, tty = SCD). Drug1 is resolved to spironolactone, Drug2 is resolved to warfarin and interaction asserted in DrugBank between Spironolactone and Warfarin.

Drug1 (rxcui = 104208, name = 2 ML digoxin 0.25 MG/ML Injection, tty = SCD). Drug2 (rxcui = 200031, name = carvedilol 6.25 MG Oral Tablet, tty = SCD). Drug1 is resolved to digoxin, Drug2 is resolved to carvedilol and interaction asserted in DrugBank between Digoxin and Carvedilol.

Drug1 (rxcui = 855312, name = warfarin sodium 2.5 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 860975, name = 24 HR metformin hydrochloride 500 MG Extended Release Oral Tablet, tty = SCD). Drug1 is resolved to metformin, Drug2 is resolved to warfarin and interaction asserted in DrugBank between Metformin and Warfarin.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.