Drug interactions for the following drug(s)

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Interactions between your selected drugs

Moderate

spironolactone<>bupropion

Applies to: Spironolactone 50 MG Oral Tablet <> Wellbutrin XL 300 MG 24HR Extended Release Oral Tablet

Spironolactone may increase the excretion rate of Bupropion which could result in a lower serum level and potentially a reduction in efficacy.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Interactions between your selected drugs

Moderate

spironolactone<>bupropion

Applies to: Spironolactone 50 MG Oral Tablet <> Wellbutrin XL 300 MG 24HR Extended Release Oral Tablet

Drug1 (rxcui = 198223, name = spironolactone 50 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 993564, name = 24 HR bupropion hydrochloride 300 MG Extended Release Oral Tablet [Wellbutrin], tty = SBD). Drug1 is resolved to spironolactone, Drug2 is resolved to bupropion and interaction asserted in DrugBank between Spironolactone and Bupropion.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

DrugInteractionChecker.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex® (updated Sep 28th, 2016), Cerner Multum™ (updated Oct 2nd, 2016), Wolters Kluwer™ (updated Oct 1st, 2016) and others. To view content sources and attributions, please refer to our editorial policy.