Drug interactions for the following drug(s)

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Interactions between your selected drugs

Moderate

Amitriptyline<>Orphenadrine

Applies to: Amitriptyline Hydrochloride 25 MG Oral Tablet <> orphenadrine citrate 100 MG 12 HR Extended Release Oral Tablet

Amitriptyline may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Interactions between your selected drugs

Moderate

Amitriptyline<>Orphenadrine

Applies to: Amitriptyline Hydrochloride 25 MG Oral Tablet <> orphenadrine citrate 100 MG 12 HR Extended Release Oral Tablet

Drug1 (rxcui = 856834, name = Amitriptyline Hydrochloride 25 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 994521, name = 12 HR Orphenadrine Citrate 100 MG Extended Release Oral Tablet, tty = SCD). Drug1 is resolved to Amitriptyline, Drug2 is resolved to Orphenadrine and interaction asserted in DrugBank between Amitriptyline and Orphenadrine.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

DrugInteractionChecker.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex® (updated Sep 28th, 2016), Cerner Multum™ (updated Oct 2nd, 2016), Wolters Kluwer™ (updated Oct 1st, 2016) and others. To view content sources and attributions, please refer to our editorial policy.