Drug interactions for the following drug(s)

Interactions between your selected drugs

Allopurinol may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.

The metabolism of Rivaroxaban can be increased when combined with Phenobarbital.

The metabolism of Phenytoin can be decreased when combined with Allopurinol.

The metabolism of Rivaroxaban can be increased when combined with Pantoprazole.

The serum concentration of Phenytoin can be increased when it is combined with Pantoprazole.

levothyroxine<>rivaroxaban

Applies to: SYNTHROID 150 MCG Oral Tablet <> Xarelto 15 MG Oral Tablet

The metabolism of Levothyroxine can be decreased when combined with Rivaroxaban.

The serum concentration of Phenobarbital can be increased when it is combined with Pantoprazole.

Pantoprazole can cause a decrease in the absorption of Levothyroxine resulting in a reduced serum concentration and potentially a decrease in efficacy.

The serum concentration of Phenytoin can be decreased when it is combined with Levothyroxine.

The metabolism of Rivaroxaban can be increased when combined with Phenytoin.

The serum concentration of Phenobarbital can be decreased when it is combined with Levothyroxine.

Pantoprazole may decrease the excretion rate of Allopurinol which could result in a higher serum level.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Interactions between your selected drugs

Drug1 (rxcui = 197320, name = Allopurinol 300 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 1232084, name = rivaroxaban 15 MG Oral Tablet [Xarelto], tty = SBD). Drug1 is resolved to Allopurinol, Drug2 is resolved to rivaroxaban and interaction asserted in DrugBank between Allopurinol and Rivaroxaban.

Drug1 (rxcui = 198086, name = Phenobarbital 16.2 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 1232084, name = rivaroxaban 15 MG Oral Tablet [Xarelto], tty = SBD). Drug1 is resolved to Phenobarbital, Drug2 is resolved to rivaroxaban and interaction asserted in DrugBank between Phenobarbital and Rivaroxaban.

Drug1 (rxcui = 197320, name = Allopurinol 300 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 1670351, name = 2 ML Phenytoin sodium 50 MG/ML Injection, tty = SCD). Drug1 is resolved to Allopurinol, Drug2 is resolved to Phenytoin and interaction asserted in DrugBank between Allopurinol and Phenytoin.

Drug1 (rxcui = 314200, name = pantoprazole 40 MG Delayed Release Oral Tablet, tty = SCD). Drug2 (rxcui = 1232084, name = rivaroxaban 15 MG Oral Tablet [Xarelto], tty = SBD). Drug1 is resolved to pantoprazole, Drug2 is resolved to rivaroxaban and interaction asserted in DrugBank between Pantoprazole and Rivaroxaban.

Drug1 (rxcui = 314200, name = pantoprazole 40 MG Delayed Release Oral Tablet, tty = SCD). Drug2 (rxcui = 1670351, name = 2 ML Phenytoin sodium 50 MG/ML Injection, tty = SCD). Drug1 is resolved to Phenytoin, Drug2 is resolved to pantoprazole and interaction asserted in DrugBank between Phenytoin and Pantoprazole.

levothyroxine<>rivaroxaban

Applies to: SYNTHROID 150 MCG Oral Tablet <> Xarelto 15 MG Oral Tablet

Drug1 (rxcui = 966201, name = Levothyroxine Sodium 0.15 MG Oral Tablet [Synthroid], tty = SBD). Drug2 (rxcui = 1232084, name = rivaroxaban 15 MG Oral Tablet [Xarelto], tty = SBD). Drug1 is resolved to levothyroxine, Drug2 is resolved to rivaroxaban and interaction asserted in DrugBank between Levothyroxine and Rivaroxaban.

Drug1 (rxcui = 198086, name = Phenobarbital 16.2 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 314200, name = pantoprazole 40 MG Delayed Release Oral Tablet, tty = SCD). Drug1 is resolved to Phenobarbital, Drug2 is resolved to pantoprazole and interaction asserted in DrugBank between Phenobarbital and Pantoprazole.

Drug1 (rxcui = 314200, name = pantoprazole 40 MG Delayed Release Oral Tablet, tty = SCD). Drug2 (rxcui = 966201, name = Levothyroxine Sodium 0.15 MG Oral Tablet [Synthroid], tty = SBD). Drug1 is resolved to levothyroxine, Drug2 is resolved to pantoprazole and interaction asserted in DrugBank between Levothyroxine and Pantoprazole.

Drug1 (rxcui = 966201, name = Levothyroxine Sodium 0.15 MG Oral Tablet [Synthroid], tty = SBD). Drug2 (rxcui = 1670351, name = 2 ML Phenytoin sodium 50 MG/ML Injection, tty = SCD). Drug1 is resolved to Phenytoin, Drug2 is resolved to levothyroxine and interaction asserted in DrugBank between Phenytoin and Levothyroxine.

Drug1 (rxcui = 1232084, name = rivaroxaban 15 MG Oral Tablet [Xarelto], tty = SBD). Drug2 (rxcui = 1670351, name = 2 ML Phenytoin sodium 50 MG/ML Injection, tty = SCD). Drug1 is resolved to Phenytoin, Drug2 is resolved to rivaroxaban and interaction asserted in DrugBank between Phenytoin and Rivaroxaban.

Drug1 (rxcui = 198086, name = Phenobarbital 16.2 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 966201, name = Levothyroxine Sodium 0.15 MG Oral Tablet [Synthroid], tty = SBD). Drug1 is resolved to Phenobarbital, Drug2 is resolved to levothyroxine and interaction asserted in DrugBank between Phenobarbital and Levothyroxine.

Drug1 (rxcui = 197320, name = Allopurinol 300 MG Oral Tablet, tty = SCD). Drug2 (rxcui = 314200, name = pantoprazole 40 MG Delayed Release Oral Tablet, tty = SCD). Drug1 is resolved to Allopurinol, Drug2 is resolved to pantoprazole and interaction asserted in DrugBank between Allopurinol and Pantoprazole.

No other interactions were found between your selected drugs.

Note: this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.